The activity-dependence of synaptic plasticity is captured in the aphorism which is often used to summarize Hebbian theory: "neurons that fire together, wire together"/"neurons that fire out of sync, fail to link". If two nearby neurons often produce an impulse in close temporal proximity, their functional properties may converge. Conversely, neurons that are not regularly activated simultaneously may be less likely to functionally converge. Source: Wikipedia.
A Cognitive Neuroscientist by training, David Vago has close to 20 years of experience with mindfulness practice and teaching, and over a decade conducting translational neuroimaging, cognitive, and clinical research on the basic mechanisms and therapeutic relevance of mindfulness and associated meditation/contemplative practices. Through his research, Dr. Vago focuses on one basic question – “What are the basic neurobiological and physiological components that constitute adaptive mind-brain-body interactions and their therapeutic relevance in psychiatric settings?”